Fluorophore ATCUN complexes: combining agent and probe for oxidative DNA cleavage.
نویسندگان
چکیده
DNA can be oxidatively cleaved by copper complexes of the ATCUN peptide (amino terminal Cu(II)- and Ni(II)-binding motif). In order to investigate the fate of the metal ion throughout this process, we have exploited quenching/dequenching effects of conjugated fluorophores.
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 62 شماره
صفحات -
تاریخ انتشار 2015